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Chemical structure of SFI003

GC73188

SFI003

Also known as N-[(E)-1-(1H-benzimidazol-2-yl)ethylideneamino]-4-(4-methoxyphenyl)-1,3-thiazol-2-amine

SFI003 is a SRSF3 inhibitor that drives CRC cell apoptosis via the SRSF3/DHCR24/ROS axis and exhibits potent antitumor effects both in vitro and in vivo

ChemicalCAS2361332-90-1MW363.44FormulaC19H17N5OS
CAS number
2361332-90-1
Molecular weight
363.44
Formula
C19H17N5OS
Solubility
DMSO ： 125 mg/mL (343·94 mM; Need ultrasonic)
InChIKey
QGFYENXFCHRFJF-FSJBWODESA-N
Catalogue number
GC73188
Brand
GLPBIO
Computed properties PubChem CID 141745171 · XLogP 4.7 · TPSA 103 Ų · H-bond donors 2
XLogP
4.7
TPSA
103 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
26

SMILES C/C(=N\NC1=NC(=CS1)C2=CC=C(C=C2)OC)/C3=NC4=CC=CC=C4N3

Computed descriptors from PubChem (CID 141745171), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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