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Chemical structure of SF2523

GC19328

SF2523

Also known as 3-(2,3-dihydro-1,4-benzodioxin-6-yl)-5-morpholin-4-ylthieno[3,2-b]pyran-7-one

SF2523 is a highly selective and potent inhibitor of PI3K with IC50s of 34 nM, 158 nM, 9 nM, 241 nM and 280 nM for PI3Kα, PI3Kγ, DNA-PK, BRD4 and mTOR, respectively

ChemicalCAS1174428-47-7MW371.41FormulaC19H17NO5S
CAS number
1174428-47-7
Molecular weight
371.41
Formula
C19H17NO5S
Solubility
DMSO ： ≥ 30 mg/mL (80·77 mM)
InChIKey
BYTKNUOMWLJVNQ-UHFFFAOYSA-N
Catalogue number
GC19328
Brand
GLPBIO
Computed properties PubChem CID 44180156 · XLogP 2.9 · TPSA 85.5 Ų · H-bond donors 0
XLogP
2.9
TPSA
85.5 Ų
H-bond donors
0
H-bond acceptors
7
Rotatable bonds
2
Heavy atoms
26

SMILES C1COCCN1C2=CC(=O)C3=C(O2)C(=CS3)C4=CC5=C(C=C4)OCCO5

Computed descriptors from PubChem (CID 44180156), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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