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Chemical structure of Thalidomide-5-PEG3-NH2 hydrochloride

GC73071

Thalidomide-5-PEG3-NH2 hydrochloride

Also known as 5-[2-[2-(2-aminoethoxy)ethoxy]ethoxy]-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride

Thalidomide-5-PEG3-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology

ChemicalCAS2761385-81-1MW441.86FormulaC19H24ClN3O7
CAS number
2761385-81-1
Molecular weight
441.86
Formula
C19H24ClN3O7
InChIKey
GBYYYUKJOCCKAV-UHFFFAOYSA-N
Catalogue number
GC73071
Brand
GLPBIO
Computed properties PubChem CID 166428255 · TPSA 137 Ų · H-bond donors 3 · H-bond acceptors 8
TPSA
137 Ų
H-bond donors
3
H-bond acceptors
8
Rotatable bonds
10
Heavy atoms
30

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C=C(C=C3)OCCOCCOCCN.Cl

Computed descriptors from PubChem (CID 166428255), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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