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Chemical structure of Thalidomide-O-C6-NH2

GC67478

Thalidomide-O-C6-NH2

Also known as 4-(6-aminohexoxy)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione

Thalidomide-O-C6-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology

ChemicalCAS1957235-98-1MW373.4FormulaC19H23N3O5
CAS number
1957235-98-1
Molecular weight
373.4
Formula
C19H23N3O5
InChIKey
QPKPIBLEXSCVSO-UHFFFAOYSA-N
Catalogue number
GC67478
Brand
GLPBIO
Computed properties PubChem CID 121439719 · XLogP 0.8 · TPSA 119 Ų · H-bond donors 2
XLogP
0.8
TPSA
119 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
8
Heavy atoms
27

SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)OCCCCCCN

Computed descriptors from PubChem (CID 121439719), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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