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Chemical structure of XL 188

GC72934

XL 188

Also known as N-[3-[[4-hydroxy-1-[(3R)-3-phenylbutanoyl]piperidin-4-yl]methyl]-4-oxoquinazolin-7-yl]-3-(4-methylpiperazin-1-yl)propanamide

XL 188 is a potent and selective USP7 inhibitor with IC50 values of 90 nM and 193 nM for USP7 full-length and catalytic domain enzyme, respectively

ChemicalCAS2305045-76-3MW574.71FormulaC32H42N6O4
CAS number
2305045-76-3
Molecular weight
574.71
Formula
C32H42N6O4
Solubility
DMSO ： 100 mg/mL (174·00 mM; Need ultrasonic)
InChIKey
QLBYDWATOPNXBG-XMMPIXPASA-N
Catalogue number
GC72934
Brand
GLPBIO
Computed properties PubChem CID 131953451 · XLogP 1.3 · TPSA 109 Ų · H-bond donors 2
XLogP
1.3
TPSA
109 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
9
Heavy atoms
42

SMILES C[C@H](CC(=O)N1CCC(CC1)(CN2C=NC3=C(C2=O)C=CC(=C3)NC(=O)CCN4CCN(CC4)C)O)C5=CC=CC=C5

Computed descriptors from PubChem (CID 131953451), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.