Loading...
Chemical structure of XL092

GC62266

XL092

Also known as 1-N'-(4-fluorophenyl)-1-N-[4-[7-methoxy-6-(methylcarbamoyl)quinolin-4-yl]oxyphenyl]cyclopropane-1,1-dicarboxamide

XL092 is an orally active, ATP-competitive inhibitor of multiple receptor tyrosine kinases (RTKs) including MET, VEGFR2, AXL and MER, with IC50s in cell-based assays of 15 nM, 1·6 nM, 3·4 nM, 7·2 nM respectively· XL092 exhibits anti-tumor activity· XL092 has the potential for kinase-dependent diseases and conditions research

ChemicalCAS2367004-54-2MW528.53FormulaC29H25FN4O5
CAS number
2367004-54-2
Molecular weight
528.53
Formula
C29H25FN4O5
Solubility
DMSO : 25 mg/mL (47·30 mM; Need ultrasonic)
InChIKey
JSPCKALGNNVYOO-UHFFFAOYSA-N
Catalogue number
GC62266
Brand
GLPBIO
Computed properties PubChem CID 139350422 · XLogP 4.7 · TPSA 119 Ų · H-bond donors 3
XLogP
4.7
TPSA
119 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
8
Heavy atoms
39

SMILES CNC(=O)C1=CC2=C(C=CN=C2C=C1OC)OC3=CC=C(C=C3)NC(=O)C4(CC4)C(=O)NC5=CC=C(C=C5)F

Computed descriptors from PubChem (CID 139350422), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.