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Chemical structure of NP3-562

GC71499

NP3-562

Also known as 2-[4-chloro-12-(2-hydroxypropan-2-yl)-9-oxo-5-thia-1,10,11-triazatricyclo[6.4.0.02,6]dodeca-2(6),3,7,11-tetraen-10-yl]-N-[(3R)-1-methylpiperidin-3-yl]acetamide

NP3-562 is a potent, orally active, tricyclic NLRP3 Inhibitor, with an IC50 of 214 nM

ChemicalCAS2409825-32-5MW437.94FormulaC19H24ClN5O3S
CAS number
2409825-32-5
Molecular weight
437.94
Formula
C19H24ClN5O3S
Solubility
DMSO ： 100 mg/mL (228·34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
AXAOJXUYQVCGBD-LLVKDONJSA-N
Catalogue number
GC71499
Brand
GLPBIO
Computed properties PubChem CID 146308190 · XLogP 2.3 · TPSA 118 Ų · H-bond donors 2
XLogP
2.3
TPSA
118 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
4
Heavy atoms
29

SMILES CC(C)(C1=NN(C(=O)C2=CC3=C(N21)C=C(S3)Cl)CC(=O)N[C@@H]4CCCN(C4)C)O

Computed descriptors from PubChem (CID 146308190), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.