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Chemical structure of NP10679

GC71059

NP10679

Also known as 6-[(2R)-2-hydroxy-3-[4-[4-(trifluoromethyl)phenyl]piperazin-1-yl]propoxy]-3,4-dihydro-1H-quinolin-2-one

NP10679 is a selective, pH dependent GluN2B subunit-specific N-methyl-D-aspartate (NMDA) receptor inhibitor with high oral bioavailability and good brain penetration

ChemicalCAS2914889-88-4MW449.47FormulaC23H26F3N3O3
CAS number
2914889-88-4
Molecular weight
449.47
Formula
C23H26F3N3O3
Solubility
DMSO ： 100 mg/mL (222·48 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
QJKYLYXHWSCZQT-LJQANCHMSA-N
Catalogue number
GC71059
Brand
GLPBIO
Computed properties PubChem CID 162623707 · XLogP 2.9 · TPSA 65 Ų · H-bond donors 2
XLogP
2.9
TPSA
65 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
6
Heavy atoms
32

SMILES C1CC(=O)NC2=C1C=C(C=C2)OC[C@@H](CN3CCN(CC3)C4=CC=C(C=C4)C(F)(F)F)O

Computed descriptors from PubChem (CID 162623707), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.