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Chemical structure of URAT1 inhibitor 6

GC71286

URAT1 inhibitor 6

Also known as sodium 2-[[5-bromo-4-(thiophen-2-ylmethyl)-1,2,4-triazol-3-yl]sulfanyl]acetate

URAT1 inhibitor 6 (Compound 1h) is a potent URAT1 inhibitor (IC50: 35 nM for hURAT1)

ChemicalCAS2244807-49-4MW356.19FormulaC9H7BrN3NaO2S2
CAS number
2244807-49-4
Molecular weight
356.19
Formula
C9H7BrN3NaO2S2
Solubility
DMSO : 100 mg/mL (280·75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
YOLZEFFEYBRHAT-UHFFFAOYSA-M
Catalogue number
GC71286
Brand
GLPBIO
Computed properties PubChem CID 168476139 · TPSA 124 Ų · H-bond donors 0 · H-bond acceptors 6
TPSA
124 Ų
H-bond donors
0
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
18

SMILES C1=CSC(=C1)CN2C(=NN=C2Br)SCC(=O)[O-].[Na+]

Computed descriptors from PubChem (CID 168476139), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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