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Chemical structure of URAT1&XO inhibitor 1

GC71285

URAT1&XO inhibitor 1

Also known as 5-[[5-cyano-1-(pyridin-2-ylmethyl)indole-3-carbonyl]amino]-1,3-thiazole-4-carboxylic acid

URAT1&XO inhibitor 1 (compound 29) is a dual inhibitor of both URAT1 (IC50=~10 μM) and Xanthine Oxidase (IC50=1·01 μM)

ChemicalCAS2669726-78-5MW403.41FormulaC20H13N5O3S
CAS number
2669726-78-5
Molecular weight
403.41
Formula
C20H13N5O3S
Solubility
DMSO : 100 mg/mL (247·89 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
YUGFHWXZQLEUKC-UHFFFAOYSA-N
Catalogue number
GC71285
Brand
GLPBIO
Computed properties PubChem CID 168476138 · XLogP 2.9 · TPSA 149 Ų · H-bond donors 2
XLogP
2.9
TPSA
149 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
5
Heavy atoms
29

SMILES C1=CC=NC(=C1)CN2C=C(C3=C2C=CC(=C3)C#N)C(=O)NC4=C(N=CS4)C(=O)O

Computed descriptors from PubChem (CID 168476138), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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