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Chemical structure of JAK-IN-24

GC71213

JAK-IN-24

Also known as 1-[(2S,5R)-2-methyl-5-[[5-(2-prop-2-ynoxyethyl)-7H-pyrrolo[2,3-d]pyrimidin-4-yl]amino]piperidin-1-yl]prop-2-en-1-one

JAK-IN-24 is a JAK inhibitor, with IC50s of 0·534 and 24 nM at the presence of 4 μM or 1mM ATP, respectively

ChemicalCAS2042629-43-4MW367.44FormulaC20H25N5O2
CAS number
2042629-43-4
Molecular weight
367.44
Formula
C20H25N5O2
Solubility
DMSO ： 100 mg/mL (272·15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
OQQBLYFXQMNSIZ-GOEBONIOSA-N
Catalogue number
GC71213
Brand
GLPBIO
Computed properties PubChem CID 122673818 · XLogP 2.3 · TPSA 83.1 Ų · H-bond donors 2
XLogP
2.3
TPSA
83.1 Ų
H-bond donors
2
H-bond acceptors
5
Rotatable bonds
7
Heavy atoms
27

SMILES C[C@H]1CC[C@H](CN1C(=O)C=C)NC2=NC=NC3=C2C(=CN3)CCOCC#C

Computed descriptors from PubChem (CID 122673818), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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