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Chemical structure of JAK-IN-14

GC63448

JAK-IN-14

Also known as N-[5-[4-(cyanomethyl)-2-fluorophenyl]imidazo[1,2-a]pyridin-2-yl]cyclopropanecarboxamide

JAK-IN-14 is a potent and selective JAK1 inhibitor, with an IC50 of ＜5 μM

ChemicalCAS1973485-06-1MW334.35FormulaC19H15FN4O
CAS number
1973485-06-1
Molecular weight
334.35
Formula
C19H15FN4O
Solubility
DMSO ： 10·5 mg/mL (31·40 mM; ultrasonic and warming and heat to 60°C)
InChIKey
MQLCYDOEKWSOBQ-UHFFFAOYSA-N
Catalogue number
GC63448
Brand
GLPBIO
Computed properties PubChem CID 122462783 · XLogP 3.1 · TPSA 70.2 Ų · H-bond donors 1
XLogP
3.1
TPSA
70.2 Ų
H-bond donors
1
H-bond acceptors
4
Rotatable bonds
4
Heavy atoms
25

SMILES C1CC1C(=O)NC2=CN3C(=N2)C=CC=C3C4=C(C=C(C=C4)CC#N)F

Computed descriptors from PubChem (CID 122462783), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.