
GC71195
DN-1289
Also known as 3-(difluoromethoxy)-5-[6-(3,3-difluoropyrrolidin-1-yl)-2-[(1S,4S)-2-oxa-5-azabicyclo[2.2.1]heptan-5-yl]pyrimidin-4-yl]pyrazin-2-amine
DN-1289 is an orally active and selective inhibitor of dual leucine zipper kinase (DLK; IC50=17 nM) and leucine zipper-bearing kinase (LZK; IC50=40 nM)
ChemicalCAS3026597-15-6MW441.38FormulaC18H19F4N7O2
- CAS number
- 3026597-15-6
- Molecular weight
- 441.38
- Formula
- C18H19F4N7O2
- InChIKey
- AVWDJSXSWJBVBP-UWVGGRQHSA-N
- Catalogue number
- GC71195
- Brand
- GLPBIO
Computed properties PubChem CID 167312371 · XLogP 2.3 · TPSA 103 Ų · H-bond donors 1
- XLogP
- 2.3
- TPSA
- 103 Ų
- H-bond donors
- 1
- H-bond acceptors
- 13
- Rotatable bonds
- 5
- Heavy atoms
- 31
SMILES C1CN(CC1(F)F)C2=NC(=NC(=C2)C3=CN=C(C(=N3)OC(F)F)N)N4C[C@@H]5C[C@H]4CO5
Computed descriptors from PubChem (CID 167312371), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il