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Chemical structure of DO34

GC31446

DO34

Also known as tert-butyl 3-benzyl-4-[4-[4-(trifluoromethoxy)phenyl]triazole-1-carbonyl]piperazine-1-carboxylate

DO34 is a highly potent, selective and centrally active diacylglycerol lipase (DAGL) inhibitor, with an IC50 of 6 nM for DAGLα conversion of SAG to 2-AG, and an IC50 for DAGLβ

ChemicalCAS1848233-58-8MW531.53FormulaC26H28F3N5O4
CAS number
1848233-58-8
Molecular weight
531.53
Formula
C26H28F3N5O4
Solubility
DMSO ： ≥ 100 mg/mL (188·14 mM)
InChIKey
CQGMWUWJVBKTRM-UHFFFAOYSA-N
Catalogue number
GC31446
Brand
GLPBIO
Computed properties PubChem CID 129188708 · XLogP 5.1 · TPSA 89.8 Ų · H-bond donors 0
XLogP
5.1
TPSA
89.8 Ų
H-bond donors
0
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
38

SMILES CC(C)(C)OC(=O)N1CCN(C(C1)CC2=CC=CC=C2)C(=O)N3C=C(N=N3)C4=CC=C(C=C4)OC(F)(F)F

Computed descriptors from PubChem (CID 129188708), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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