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Chemical structure of SZM679

GC71180

SZM679

Also known as N-[5-fluoro-6-[4-fluoro-3-[[2-[3-(trifluoromethoxy)phenyl]acetyl]amino]phenoxy]-1,3-benzothiazol-2-yl]-3-oxocyclobutane-1-carboxamide

SZM679 is a potent, orally active and selective RIPK1 inhibitor with Kd values of 8·6 nM and >5000 nM for RIPK1 and RIPK3, respectively

ChemicalCAS3027645-52-6MW591.51FormulaC27H18F5N3O5S
CAS number
3027645-52-6
Molecular weight
591.51
Formula
C27H18F5N3O5S
Solubility
DMSO ： 125 mg/mL (211·32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
OFQHMPFSITXRSS-UHFFFAOYSA-N
Catalogue number
GC71180
Brand
GLPBIO
Computed properties PubChem CID 166176959 · XLogP 5 · TPSA 135 Ų · H-bond donors 2
XLogP
5
TPSA
135 Ų
H-bond donors
2
H-bond acceptors
12
Rotatable bonds
8
Heavy atoms
41

SMILES C1C(CC1=O)C(=O)NC2=NC3=CC(=C(C=C3S2)OC4=CC(=C(C=C4)F)NC(=O)CC5=CC(=CC=C5)OC(F)(F)F)F

Computed descriptors from PubChem (CID 166176959), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.