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Chemical structure of PROTAC PTPN2 degrader-1

GC71045

PROTAC PTPN2 degrader-1

Also known as 2-[4-[1-(2,6-dioxopiperidin-3-yl)-3-methyl-2-oxobenzimidazol-5-yl]phenyl]-N-[5-fluoro-7-hydroxy-6-(1,1,4-trioxo-1,2,5-thiadiazolidin-2-yl)naphthalen-2-yl]acetamide

PROTAC PTPN2 degrader-1 (compound example 77) is a potent PTPN2 degrader

ChemicalCAS2655638-07-4MW686.67FormulaC33H27FN6O8S
CAS number
2655638-07-4
Molecular weight
686.67
Formula
C33H27FN6O8S
Solubility
DMSO : 100 mg/mL (145·63 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
SVEZXFBVLPICRX-UHFFFAOYSA-N
Catalogue number
GC71045
Brand
GLPBIO
Computed properties PubChem CID 156507515 · XLogP 2 · TPSA 194 Ų · H-bond donors 4
XLogP
2
TPSA
194 Ų
H-bond donors
4
H-bond acceptors
10
Rotatable bonds
6
Heavy atoms
49

SMILES CN1C2=C(C=CC(=C2)C3=CC=C(C=C3)CC(=O)NC4=CC5=CC(=C(C(=C5C=C4)F)N6CC(=O)NS6(=O)=O)O)N(C1=O)C7CCC(=O)NC7=O

Computed descriptors from PubChem (CID 156507515), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.