Loading...
Chemical structure of Dyrk1A-IN-3

GC70985

Dyrk1A-IN-3

Also known as N-methyl-N-(3-methylphenyl)-4-pyrazolo[1,5-b]pyridazin-3-ylpyrimidin-2-amine

Dyrk1A-IN-3 (Compound 8b), a highly selective dual-specificity tyrosine-regulated kinase 1A (DYRK1A)inhibitor, maintains high levels of DYRK1A binding affinity (IC50=76 nM)

ChemicalCAS2493976-27-3MW316.36FormulaC18H16N6
CAS number
2493976-27-3
Molecular weight
316.36
Formula
C18H16N6
Solubility
DMSO ： 100 mg/mL (316·10 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
XOBINHQHMGZFDI-UHFFFAOYSA-N
Catalogue number
GC70985
Brand
GLPBIO
Computed properties PubChem CID 156011155 · XLogP 3 · TPSA 59.2 Ų · H-bond donors 0
XLogP
3
TPSA
59.2 Ų
H-bond donors
0
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
24

SMILES CC1=CC(=CC=C1)N(C)C2=NC=CC(=N2)C3=C4C=CC=NN4N=C3

Computed descriptors from PubChem (CID 156011155), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.