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Chemical structure of PF-3882845

GC70603

PF-3882845

Also known as (3S,3aR)-2-(3-chloro-4-cyanophenyl)-3-cyclopentyl-3,3a,4,5-tetrahydrobenzo[g]indazole-7-carboxylic acid

PF-3882845 is a remarkably high affinity selective and orally efficacious mineralocorticoid receptor (MR binding IC50=2·7 nM) antagonist for hypertension and nephropathy

ChemicalCAS1023650-66-9MW419.9FormulaC24H22ClN3O2
CAS number
1023650-66-9
Molecular weight
419.9
Formula
C24H22ClN3O2
Solubility
DMSO ： 10 mg/mL (23·82 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
XNULRSOGWPFPBL-REWPJTCUSA-N
Catalogue number
GC70603
Brand
GLPBIO
Computed properties PubChem CID 46871935 · XLogP 5.7 · TPSA 76.7 Ų · H-bond donors 1
XLogP
5.7
TPSA
76.7 Ų
H-bond donors
1
H-bond acceptors
5
Rotatable bonds
3
Heavy atoms
30

SMILES C1CCC(C1)[C@H]2[C@H]3CCC4=C(C3=NN2C5=CC(=C(C=C5)C#N)Cl)C=CC(=C4)C(=O)O

Computed descriptors from PubChem (CID 46871935), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.