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Chemical structure of VU0364289

GC70503

VU0364289

Also known as 2-[4-(2-phenylmethoxyacetyl)piperazin-1-yl]benzonitrile

VU0364289 is a highly selective mGlu5 positive allosteric modulator (PAM) (binds to the MPEP site), with an EC50 of 1·6 µM

ChemicalCAS1242443-29-3MW335.4FormulaC20H21N3O2
CAS number
1242443-29-3
Molecular weight
335.4
Formula
C20H21N3O2
Solubility
DMSO ： 100 mg/mL (298·15 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
LTPGKAICNBCBPT-UHFFFAOYSA-N
Catalogue number
GC70503
Brand
GLPBIO
Computed properties PubChem CID 46865097 · XLogP 2.4 · TPSA 56.6 Ų · H-bond donors 0
XLogP
2.4
TPSA
56.6 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
5
Heavy atoms
25

SMILES C1CN(CCN1C2=CC=CC=C2C#N)C(=O)COCC3=CC=CC=C3

Computed descriptors from PubChem (CID 46865097), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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