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Chemical structure of VU0360172

GC64513

VU0360172

Also known as N-cyclobutyl-6-[2-(3-fluorophenyl)ethynyl]pyridine-3-carboxamide

VU0360172 is a potent and selective mGlu5 receptor positive allosteric modulator with an EC50 value of 16 nM and a Ki of 195 nM, respectively

ChemicalCAS1310012-12-4MW294.32FormulaC18H15FN2O
CAS number
1310012-12-4
Molecular weight
294.32
Formula
C18H15FN2O
Solubility
DMSO ： 83·33 mg/mL (283·13 mM; Need ultrasonic)
InChIKey
NEMHWVUKNWAKTM-UHFFFAOYSA-N
Catalogue number
GC64513
Brand
GLPBIO
Computed properties PubChem CID 53318624 · XLogP 3.2 · TPSA 42 Ų · H-bond donors 1
XLogP
3.2
TPSA
42 Ų
H-bond donors
1
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
22

SMILES C1CC(C1)NC(=O)C2=CN=C(C=C2)C#CC3=CC(=CC=C3)F

Computed descriptors from PubChem (CID 53318624), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.