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Chemical structure of JNJ-49095397

GC70499

JNJ-49095397

Also known as N-[4-[[4-[[3-tert-butyl-1-(4-methylphenyl)pyrazol-5-yl]carbamoylamino]naphthalen-1-yl]oxymethyl]-2-pyridinyl]-2-methoxyacetamide

JNJ-49095397 (RV568) is an inhaled narrow-spectrum kinase inhibitor (NSKI) against both the α and γ isoforms of p38 MAPK

ChemicalCAS1220626-82-3MW592.69FormulaC34H36N6O4
CAS number
1220626-82-3
Molecular weight
592.69
Formula
C34H36N6O4
Solubility
DMSO ： 100 mg/mL (168·72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
RTDCVLCTBQDLBW-UHFFFAOYSA-N
Catalogue number
GC70499
Brand
GLPBIO
Computed properties PubChem CID 45109868 · XLogP 5.9 · TPSA 119 Ų · H-bond donors 3
XLogP
5.9
TPSA
119 Ų
H-bond donors
3
H-bond acceptors
6
Rotatable bonds
10
Heavy atoms
44

SMILES CC1=CC=C(C=C1)N2C(=CC(=N2)C(C)(C)C)NC(=O)NC3=CC=C(C4=CC=CC=C43)OCC5=CC(=NC=C5)NC(=O)COC

Computed descriptors from PubChem (CID 45109868), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.