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Chemical structure of TPN729MA

GC70431

TPN729MA

Also known as (Z)-but-2-enedioic acid;N-methyl-3-(1-methyl-7-oxo-3-propyl-6H-pyrazolo[4,5-d]pyrimidin-5-yl)-4-propoxy-N-(2-pyrrolidin-1-ylethyl)benzenesulfonamide

TPN729MA (TPN729 maleate) is a selective phosphodiesterase type 5 (PDE5) inhibitor with an IC50 value of 2·28 nM

ChemicalCAS1422955-52-9MW632.73FormulaC29H40N6O8S
CAS number
1422955-52-9
Molecular weight
632.73
Formula
C29H40N6O8S
Solubility
DMSO ： 25 mg/mL (39·51 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
InChIKey
CNCJOFPBSNINND-BTJKTKAUSA-N
Catalogue number
GC70431
Brand
GLPBIO
Computed properties PubChem CID 136266251 · TPSA 192 Ų · H-bond donors 3 · H-bond acceptors 12
TPSA
192 Ų
H-bond donors
3
H-bond acceptors
12
Rotatable bonds
13
Heavy atoms
44

SMILES CCCC1=NN(C2=C1N=C(NC2=O)C3=C(C=CC(=C3)S(=O)(=O)N(C)CCN4CCCC4)OCCC)C.C(=C\C(=O)O)\C(=O)O

Computed descriptors from PubChem (CID 136266251), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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