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Chemical structure of Zetomipzomib maleate

GC70395

Zetomipzomib maleate

Also known as (Z)-but-2-enedioic acid;(2S,3R)-N-[(2S)-3-(cyclopenten-1-yl)-1-[(2R)-2-methyloxiran-2-yl]-1-oxopropan-2-yl]-3-hydroxy-3-(4-methoxyphenyl)-2-[[(2S)-2-[(2-morpholin-4-ylacetyl)amino]propanoyl]amino]propanamide

Zetomipzomib (KZR-616) maleate, a first-in-class immunoproteasome inhibitor, selectively targets the LMP7 (IC50: 39/57 nM=hLMP7/mLMP7) and LMP2 (IC50: 131/179 nM=hLMP2/mLMP2) subunits of the immunoproteasome

ChemicalCAS2170983-62-5MW702.75FormulaC34H46N4O12
CAS number
2170983-62-5
Molecular weight
702.75
Formula
C34H46N4O12
Solubility
DMSO ： 250 mg/mL (355·75 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO); H2O ： 50 mg/mL (71·15 mM; Need ultrasonic)
InChIKey
HVKAUVYFVFFXLW-MTOCQVLVSA-N
Catalogue number
GC70395
Brand
GLPBIO
Computed properties PubChem CID 162640583 · TPSA 233 Ų · H-bond donors 6 · H-bond acceptors 13
TPSA
233 Ų
H-bond donors
6
H-bond acceptors
13
Rotatable bonds
16
Heavy atoms
50

SMILES C[C@@H](C(=O)N[C@@H]([C@@H](C1=CC=C(C=C1)OC)O)C(=O)N[C@@H](CC2=CCCC2)C(=O)[C@]3(CO3)C)NC(=O)CN4CCOCC4.C(=C\C(=O)O)\C(=O)O

Computed descriptors from PubChem (CID 162640583), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.