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Chemical structure of Vulolisib

GC70138

Vulolisib

Also known as (2S)-2-[[2-[(4R)-4-(difluoromethyl)-2-oxo-1,3-thiazolidin-3-yl]-5,6-dihydroimidazo[1,2-d][1,4]benzoxazepin-9-yl]amino]propanamide

Vulolisib is an effective and orally active phosphoinositide 3-kinase (PI3K) inhibitor with IC50 values of 0·2 nM, 168 nM, 90 nM, and 49 nM for PI3Kα, PI3Kβ, PI3Kγ, and PI3Kδ respectively· It has anti-proliferative activity against cancer cells and also exhibits anti-tumor activity

ChemicalCAS2390105-79-8MW423.44FormulaC18H19F2N5O3S
CAS number
2390105-79-8
Molecular weight
423.44
Formula
C18H19F2N5O3S
InChIKey
KEEKMOIRJUWKNK-CABZTGNLSA-N
Catalogue number
GC70138
Brand
GLPBIO
Computed properties PubChem CID 146267141 · XLogP 2 · TPSA 128 Ų · H-bond donors 2
XLogP
2
TPSA
128 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
29

SMILES C[C@@H](C(=O)N)NC1=CC2=C(C=C1)C3=NC(=CN3CCO2)N4[C@@H](CSC4=O)C(F)F

Computed descriptors from PubChem (CID 146267141), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.