Loading...
Chemical structure of Vps34-IN-2

GC32932

Vps34-IN-2

Also known as (8S)-2-[(3R)-3-methylmorpholin-4-yl]-9-(3-methyl-2-oxobutyl)-8-(trifluoromethyl)-7,8-dihydro-6H-pyrimido[1,2-a]pyrimidin-4-one

Vps34-IN-2 is a novel, potent and selective inhibitor of Vps34 with IC50s of 2 and 82 nM on the Vps34 enzymatic assay and the GFP-FYVE cellular assay, respectively· Vps34-IN-2 shows antiviral activity against SARS-CoV-2 (IC50 of 3·1 μM), HCoV-229E (IC50 of 0·7 μM) and HCoV-OC43

ChemicalCAS1523404-29-6MW402.41FormulaC18H25F3N4O3
CAS number
1523404-29-6
Molecular weight
402.41
Formula
C18H25F3N4O3
Solubility
Ethanol： 50 mg/mL (124·25 mM)
InChIKey
ITCIAOUZMPREOO-OCCSQVGLSA-N
Catalogue number
GC32932
Brand
GLPBIO
Computed properties PubChem CID 72709284 · XLogP 2 · TPSA 65.5 Ų · H-bond donors 0
XLogP
2
TPSA
65.5 Ų
H-bond donors
0
H-bond acceptors
8
Rotatable bonds
4
Heavy atoms
28

SMILES C[C@@H]1COCCN1C2=CC(=O)N3CC[C@H](N(C3=N2)CC(=O)C(C)C)C(F)(F)F

Computed descriptors from PubChem (CID 72709284), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.