GC70135
VU6019650
VU6019650 is a potent and selective M5 mAChR positive allosteric modulator (IC50=36 nM) that can be used for research on alleviating opioid use disorder (OUD)· VU6019650 has blood-brain barrier permeability and may regulate the mesolimbic dopamine reward circuit· VU6019650 can block the increase in firing rate of ventral tegmental area (VTA) dopamine neurons induced by Oxotremorine M iodide
ChemicalMW411.51FormulaC18H22FN3O3S2
- CAS number
- —
- Molecular weight
- 411.51
- Formula
- C18H22FN3O3S2
- Solubility
- DMSO ： 8·33 mg/mL (20·24 mM; ultrasonic and warming and heat to 60°C)
- Catalogue number
- GC70135
- Brand
- GLPBIO
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il