GC70131
VT02956
Also known as 3-[4-[4-(aminomethyl)piperidin-1-yl]-2-pyridin-4-ylquinazolin-8-yl]prop-2-yn-1-ol
VT02956 is a LATS inhibitor (IC50: 0·76 nM for LATS1 and 0·52 nM for LATS2)· It targets the Hippo signaling pathway and inhibits the growth of ER+ breast cancer cell lines and tumor organoids derived from patients, as well as ESR1 expression
ChemicalCAS2999763-09-4MW373.45FormulaC22H23N5O
- CAS number
- 2999763-09-4
- Molecular weight
- 373.45
- Formula
- C22H23N5O
- InChIKey
- KXRPXGNXQVGLIN-UHFFFAOYSA-N
- Catalogue number
- GC70131
- Brand
- GLPBIO
Computed properties PubChem CID 166642551 · XLogP 1.9 · TPSA 88.2 Ų · H-bond donors 2
- XLogP
- 1.9
- TPSA
- 88.2 Ų
- H-bond donors
- 2
- H-bond acceptors
- 6
- Rotatable bonds
- 4
- Heavy atoms
- 28
SMILES C1CN(CCC1CN)C2=NC(=NC3=C(C=CC=C32)C#CCO)C4=CC=NC=C4
Computed descriptors from PubChem (CID 166642551), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il