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Chemical structure of VT103

GC63257

VT103

Also known as N-methyl-3-(1-methylimidazol-4-yl)-4-[4-(trifluoromethyl)anilino]benzenesulfonamide

VT103, an analog of VT101, is an orally active and selective TEAD1 protein palmitoylation inhibitor· VT103 inhibits YAP/TAZ-TEAD promoted gene transcription, blocks TEAD auto-palmitoylation, and disrupts interaction between YAP/TAZ and TEAD· VT103 can be used for the research of cancer

ChemicalCAS2290608-13-6MW410.41FormulaC18H17F3N4O2S
CAS number
2290608-13-6
Molecular weight
410.41
Formula
C18H17F3N4O2S
Solubility
DMSO ： 50 mg/mL (121·83 mM; Need ultrasonic)
InChIKey
LLCVDQHLYHBAHR-UHFFFAOYSA-N
Catalogue number
GC63257
Brand
GLPBIO
Computed properties PubChem CID 137534047 · XLogP 3.1 · TPSA 84.4 Ų · H-bond donors 2
XLogP
3.1
TPSA
84.4 Ų
H-bond donors
2
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
28

SMILES CNS(=O)(=O)C1=CC(=C(C=C1)NC2=CC=C(C=C2)C(F)(F)F)C3=CN(C=N3)C

Computed descriptors from PubChem (CID 137534047), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.