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Chemical structure of VL285 Phenol

GC70121

VL285 Phenol

Also known as (2S,4R)-4-hydroxy-N-[[2-hydroxy-4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-1-[(2S)-3-methyl-2-(3-oxo-1H-isoindol-2-yl)butanoyl]pyrrolidine-2-carboxamide

VL285 Phenol is a VL285 analog with a phenol group· VL285 is a small molecule VHL ligand that can act as a degrader in the synthesis of HaloPROTAC3· VL285 can degrade HaloTag7 fusion protein (IC50=0·34 μM)

ChemicalCAS1448188-69-9MW548.65FormulaC29H32N4O5S
CAS number
1448188-69-9
Molecular weight
548.65
Formula
C29H32N4O5S
InChIKey
KNZQRBRUYSXXRG-VTZPFEBOSA-N
Catalogue number
GC70121
Brand
GLPBIO
Computed properties PubChem CID 89690874 · XLogP 3.5 · TPSA 151 Ų · H-bond donors 3
XLogP
3.5
TPSA
151 Ų
H-bond donors
3
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
39

SMILES CC1=C(SC=N1)C2=CC(=C(C=C2)CNC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)C)N4CC5=CC=CC=C5C4=O)O)O

Computed descriptors from PubChem (CID 89690874), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.