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Chemical structure of TTBK1-IN-1

GC70075

TTBK1-IN-1

Also known as (3S)-1-[1-(2-amino-6-methoxypyrimidin-4-yl)pyrrolo[3,2-c]pyridin-6-yl]-3-methylpent-1-yn-3-ol

TTBK1-IN-1 is a potent, selective, brain-penetrant inhibitor of tau tubulin kinase 1 (TTBK1) with an IC50 of 2·7 nM· TTBK1-IN-1 can be used for research on Alzheimer's disease and related disorders

ChemicalCAS2735015-60-6MW337.38FormulaC18H19N5O2
CAS number
2735015-60-6
Molecular weight
337.38
Formula
C18H19N5O2
Solubility
Ethanol ： 33·33 mg/mL (98·79 mM; ultrasonic and adjust pH to 3 with HCl)
InChIKey
HPJVZSVEIGCFJP-SFHVURJKSA-N
Catalogue number
GC70075
Brand
GLPBIO
Computed properties PubChem CID 162642653 · XLogP 1.8 · TPSA 99.1 Ų · H-bond donors 2
XLogP
1.8
TPSA
99.1 Ų
H-bond donors
2
H-bond acceptors
6
Rotatable bonds
5
Heavy atoms
25

SMILES CC[C@@](C)(C#CC1=CC2=C(C=CN2C3=CC(=NC(=N3)N)OC)C=N1)O

Computed descriptors from PubChem (CID 162642653), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

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Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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