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Chemical structure of TTA-A2

GC61358

TTA-A2

Also known as 2-(4-cyclopropylphenyl)-N-[(1R)-1-[5-(2,2,2-trifluoroethoxy)-2-pyridinyl]ethyl]acetamide

TTA-A2 is a potent, selective and orally active t-type voltage gated calcium?channel antagonist with reduced pregnane X receptor (PXR) activation

ChemicalCAS953778-63-7MW378.39FormulaC20H21F3N2O2
CAS number
953778-63-7
Molecular weight
378.39
Formula
C20H21F3N2O2
Solubility
DMSO : 100 mg/mL (264·28 mM; Need ultrasonic)
InChIKey
GEYDMBNDOVPFJL-CYBMUJFWSA-N
Catalogue number
GC61358
Brand
GLPBIO
Computed properties PubChem CID 53317097 · XLogP 4 · TPSA 51.2 Ų · H-bond donors 1
XLogP
4
TPSA
51.2 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
27

SMILES C[C@H](C1=NC=C(C=C1)OCC(F)(F)F)NC(=O)CC2=CC=C(C=C2)C3CC3

Computed descriptors from PubChem (CID 53317097), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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