Loading...
Chemical structure of TRPC6-IN-3

GC70066

TRPC6-IN-3

Also known as [4-(6-aminopyridazin-3-yl)piperidin-1-yl]-[5-(4-fluorophenoxy)-4-methoxy-2-pyridinyl]methanone

TRPC6-IN-3 (compound 17) is an orally effective inhibitor of transient receptor potential cation channel subfamily C member 6 (TRPC6)· TRPC6-IN-3 can not only regulate intracellular calcium concentration, but also modulate membrane potential by regulating cation flux including calcium and sodium ions· TRPC6-IN-3 can be used for research in the respiratory system

ChemicalCAS2311863-36-0MW423.44FormulaC22H22FN5O3
CAS number
2311863-36-0
Molecular weight
423.44
Formula
C22H22FN5O3
Solubility
DMSO ： 125 mg/mL (295·20 mM; Need ultrasonic)
InChIKey
JUALOUHZJJERQT-UHFFFAOYSA-N
Catalogue number
GC70066
Brand
GLPBIO
Computed properties PubChem CID 138674835 · XLogP 2.1 · TPSA 103 Ų · H-bond donors 1
XLogP
2.1
TPSA
103 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
5
Heavy atoms
31

SMILES COC1=CC(=NC=C1OC2=CC=C(C=C2)F)C(=O)N3CCC(CC3)C4=NN=C(C=C4)N

Computed descriptors from PubChem (CID 138674835), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.