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Chemical structure of TRPC6 inhibitor

GC13218

TRPC6 inhibitor

Also known as 4-[[(1R,2R)-2-[(3R)-3-aminopiperidin-1-yl]-2,3-dihydro-1H-inden-1-yl]oxy]-3-chlorobenzonitrile;dihydrochloride

TRPC6 inhibitor is a potent and specific TRPC6 inhibitor, inhibiting TRPC6 currents with IC50 of 7·9 nM

ChemicalCAS1333207-63-8MW440.79FormulaC21H24Cl3N3O
CAS number
1333207-63-8
Molecular weight
440.79
Formula
C21H24Cl3N3O
Solubility
DMF： 1 mg/mL,DMSO： 15 mg/mL,Ethanol： 25 mg/mL,Ethanol：PBS (pH 7·2) (1：5)： 0·16mg/mL
InChIKey
LFMYIKNZNTZSJX-IQJQELQDSA-N
Catalogue number
GC13218
Brand
GLPBIO
Computed properties PubChem CID 78357800 · TPSA 62.3 Ų · H-bond donors 3 · H-bond acceptors 4
TPSA
62.3 Ų
H-bond donors
3
H-bond acceptors
4
Rotatable bonds
3
Heavy atoms
28

SMILES C1C[C@H](CN(C1)[C@@H]2CC3=CC=CC=C3[C@H]2OC4=C(C=C(C=C4)C#N)Cl)N.Cl.Cl

Computed descriptors from PubChem (CID 78357800), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.