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Chemical structure of TP-5801

GC70047

TP-5801

Also known as 5-bromo-4-N-[2-(dimethylamino)-3-pyridinyl]-2-N-[2-methoxy-5-methyl-4-(4-methylpiperazin-1-yl)phenyl]pyrimidine-2,4-diamine

TP-5801 is an orally active inhibitor of non-receptor tyrosine kinase (TNK1) with an IC50 of 1·40 nM and exhibits anti-tumor activity

ChemicalCAS2574474-81-8MW527.46FormulaC24H31BrN8O
CAS number
2574474-81-8
Molecular weight
527.46
Formula
C24H31BrN8O
Solubility
DMSO ： 16·67 mg/mL (31·60 mM; Need ultrasonic)
InChIKey
CPJOTOBXAWKVCT-UHFFFAOYSA-N
Catalogue number
GC70047
Brand
GLPBIO
Computed properties PubChem CID 155457009 · XLogP 4.3 · TPSA 81.7 Ų · H-bond donors 2
XLogP
4.3
TPSA
81.7 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
7
Heavy atoms
34

SMILES CC1=CC(=C(C=C1N2CCN(CC2)C)OC)NC3=NC=C(C(=N3)NC4=C(N=CC=C4)N(C)C)Br

Computed descriptors from PubChem (CID 155457009), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.