Loading...
Chemical structure of TP-3654

GC19361

TP-3654

Also known as 2-[4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol

TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively

ChemicalCAS1361951-15-6MW418.46FormulaC22H25F3N4O
CAS number
1361951-15-6
Molecular weight
418.46
Formula
C22H25F3N4O
Solubility
DMSO : 50 mg/mL (119·49 mM);Water : < 0·1 mg/mL (insoluble)
InChIKey
XRNVABDYQLHODA-UHFFFAOYSA-N
Catalogue number
GC19361
Brand
GLPBIO
Computed properties PubChem CID 66598080 · XLogP 4.6 · TPSA 62.5 Ų · H-bond donors 2
XLogP
4.6
TPSA
62.5 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
4
Heavy atoms
30

SMILES CC(C)(C1CCC(CC1)NC2=NN3C(=NC=C3C4=CC(=CC=C4)C(F)(F)F)C=C2)O

Computed descriptors from PubChem (CID 66598080), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.