
GC19361
TP-3654
Also known as 2-[4-[[3-[3-(trifluoromethyl)phenyl]imidazo[1,2-b]pyridazin-6-yl]amino]cyclohexyl]propan-2-ol
TP-3654 is a second-generation Pim kinase inhibitor with Ki values of 5 and 42 nM for Pim-1 and Pim-3, respectively
ChemicalCAS1361951-15-6MW418.46FormulaC22H25F3N4O
- CAS number
- 1361951-15-6
- Molecular weight
- 418.46
- Formula
- C22H25F3N4O
- Solubility
- DMSO : 50 mg/mL (119·49 mM);Water : < 0·1 mg/mL (insoluble)
- InChIKey
- XRNVABDYQLHODA-UHFFFAOYSA-N
- Catalogue number
- GC19361
- Brand
- GLPBIO
Computed properties PubChem CID 66598080 · XLogP 4.6 · TPSA 62.5 Ų · H-bond donors 2
- XLogP
- 4.6
- TPSA
- 62.5 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Rotatable bonds
- 4
- Heavy atoms
- 30
SMILES CC(C)(C1CCC(CC1)NC2=NN3C(=NC=C3C4=CC(=CC=C4)C(F)(F)F)C=C2)O
Computed descriptors from PubChem (CID 66598080), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il