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Chemical structure of TLR9-IN-1

GC70036

TLR9-IN-1

Also known as N-[3-(dimethylamino)propyl]-1-[2-(4-methylphenyl)pyrazolo[3,4-d]pyridazin-7-yl]piperidine-4-carboxamide

TLR9-IN-1 is an effective and selective inhibitor of TLR9, with an IC50 of 7 nM for human TLR9· TLR9-IN-1 can be used to study diseases related to adverse immune responses

ChemicalCAS2226366-86-3MW421.54FormulaC23H31N7O
CAS number
2226366-86-3
Molecular weight
421.54
Formula
C23H31N7O
Solubility
DMSO : 500 mg/mL (1186·13 mM; Need ultrasonic)
InChIKey
FRMXKWKQIYLSMO-UHFFFAOYSA-N
Catalogue number
GC70036
Brand
GLPBIO
Computed properties PubChem CID 134515962 · XLogP 2.1 · TPSA 79.2 Ų · H-bond donors 1
XLogP
2.1
TPSA
79.2 Ų
H-bond donors
1
H-bond acceptors
6
Rotatable bonds
7
Heavy atoms
31

SMILES CC1=CC=C(C=C1)N2C=C3C=NN=C(C3=N2)N4CCC(CC4)C(=O)NCCCN(C)C

Computed descriptors from PubChem (CID 134515962), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.