GC63229
TL-895
Also known as 1-[4-[[[6-amino-5-(4-phenoxyphenyl)pyrimidin-4-yl]amino]methyl]-4-fluoropiperidin-1-yl]prop-2-en-1-one
TL-895 is a potent, orally active, ATP-competitive, and highly selective irreversible BTK inhibitor with an IC50 and a Ki of 1·5 nM and 11·9 nM, respectively
ChemicalCAS1415823-49-2MW447.5FormulaC25H26FN5O2
- CAS number
- 1415823-49-2
- Molecular weight
- 447.5
- Formula
- C25H26FN5O2
- Solubility
- DMSO ： 250 mg/mL (558·66 mM; Need ultrasonic)
- InChIKey
- OXOXFDSEGFLWLU-UHFFFAOYSA-N
- Catalogue number
- GC63229
- Brand
- GLPBIO
Computed properties PubChem CID 86721856 · XLogP 4.1 · TPSA 93.4 Ų · H-bond donors 2
- XLogP
- 4.1
- TPSA
- 93.4 Ų
- H-bond donors
- 2
- H-bond acceptors
- 7
- Rotatable bonds
- 7
- Heavy atoms
- 33
SMILES C=CC(=O)N1CCC(CC1)(CNC2=NC=NC(=C2C3=CC=C(C=C3)OC4=CC=CC=C4)N)F
Computed descriptors from PubChem (CID 86721856), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il