Loading...
Chemical structure of TK-129

GC70033

TK-129

Also known as 1-cyclopropyl-3-[(3R)-1-(5-propan-2-yl-1H-pyrazole-3-carbonyl)pyrrolidin-3-yl]urea

TK-129 is an orally effective, low-toxicity and potent KDM5B inhibitor (with high affinity; IC50=44 nM)

ChemicalCAS3031476-73-7MW305.38FormulaC15H23N5O2
CAS number
3031476-73-7
Molecular weight
305.38
Formula
C15H23N5O2
Solubility
DMSO ： 100 mg/mL (327·46 mM; Need ultrasonic)
InChIKey
WNSMPEBHTSITSG-LLVKDONJSA-N
Catalogue number
GC70033
Brand
GLPBIO
Computed properties PubChem CID 165412819 · XLogP 1.1 · TPSA 90.1 Ų · H-bond donors 3
XLogP
1.1
TPSA
90.1 Ų
H-bond donors
3
H-bond acceptors
3
Rotatable bonds
4
Heavy atoms
22

SMILES CC(C)C1=CC(=NN1)C(=O)N2CC[C@H](C2)NC(=O)NC3CC3

Computed descriptors from PubChem (CID 165412819), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.