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Chemical structure of TL 12-186

GC50484

TL 12-186

Also known as N-[2-[2-[2-[4-[4-[[5-chloro-4-(2-propan-2-ylsulfonylanilino)pyrimidin-2-yl]amino]phenyl]piperazin-1-yl]ethoxy]ethoxy]ethyl]-2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]acetamide

Multikinase degrading PROTAC

ChemicalCAS2250025-88-6MW931.46FormulaC44H51ClN10O9S
CAS number
2250025-88-6
Molecular weight
931.46
Formula
C44H51ClN10O9S
Solubility
Soluble in DMSO
InChIKey
YNGWQHGVASHCBK-UHFFFAOYSA-N
Catalogue number
GC50484
Brand
GLPBIO
Computed properties PubChem CID 134812843 · XLogP 4.6 · TPSA 242 Ų · H-bond donors 5
XLogP
4.6
TPSA
242 Ų
H-bond donors
5
H-bond acceptors
16
Rotatable bonds
20
Heavy atoms
65

SMILES CC(C)S(=O)(=O)C1=CC=CC=C1NC2=NC(=NC=C2Cl)NC3=CC=C(C=C3)N4CCN(CC4)CCOCCOCCNC(=O)CNC5=CC=CC6=C5C(=O)N(C6=O)C7CCC(=O)NC7=O

Computed descriptors from PubChem (CID 134812843), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.