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Chemical structure of TGFβ1-IN-1

GC70021

TGFβ1-IN-1

Also known as N-cyclopentyl-3-[[(E)-3-(4-methoxyphenyl)prop-2-enoyl]amino]benzamide

TGFβ1-IN-1 is a highly effective, orally active transforming growth factor β1 (TGF-β1) specific inhibitor that can significantly block the TGF-β1 signaling pathway and inhibit the upregulation of fibrosis-related proteins (such as α-smooth muscle actin and fibronectin) mediated by it· It is suitable for the mechanism research and treatment development of fibroproliferative diseases such as liver fibrosis

ChemicalCAS2348795-14-0MW364.44FormulaC22H24N2O3
CAS number
2348795-14-0
Molecular weight
364.44
Formula
C22H24N2O3
Solubility
DMSO ： 100 mg/mL (274·39 mM; Need ultrasonic)
InChIKey
TZERIKHLXBOLFD-SDNWHVSQSA-N
Catalogue number
GC70021
Brand
GLPBIO
Computed properties PubChem CID 165412786 · XLogP 3.7 · TPSA 67.4 Ų · H-bond donors 2
XLogP
3.7
TPSA
67.4 Ų
H-bond donors
2
H-bond acceptors
3
Rotatable bonds
6
Heavy atoms
27

SMILES COC1=CC=C(C=C1)/C=C/C(=O)NC2=CC=CC(=C2)C(=O)NC3CCCC3

Computed descriptors from PubChem (CID 165412786), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.