GC69910
SKF 83959
Also known as 9-chloro-3-methyl-5-(3-methylphenyl)-1,2,4,5-tetrahydro-3-benzazepine-7,8-diol
SKF83959 is an effective selective partial agonist of dopamine D1-like receptors· The Ki values for rat D1, D5, D2 and D3 are 1·18, 7·56, 920 and 399 nM respectively· SKF83959 is also an effective sigma (σ)-1 receptor allosteric modulator· It belongs to the benzazepine family and has been shown to improve cognitive dysfunction· SKF83959 can be used in research on Alzheimer's disease and depression
ChemicalCAS80751-85-5MW317.81FormulaC18H20ClNO2
- CAS number
- 80751-85-5
- Molecular weight
- 317.81
- Formula
- C18H20ClNO2
- Solubility
- DMSO ： ≥ 100 mg/mL (314·65 mM)
- InChIKey
- JXMYTVOBSFOHAF-UHFFFAOYSA-N
- Catalogue number
- GC69910
- Brand
- GLPBIO
Computed properties PubChem CID 133538 · XLogP 3.6 · TPSA 43.7 Ų · H-bond donors 2
- XLogP
- 3.6
- TPSA
- 43.7 Ų
- H-bond donors
- 2
- H-bond acceptors
- 3
- Rotatable bonds
- 1
- Heavy atoms
- 22
SMILES CC1=CC(=CC=C1)C2CN(CCC3=C(C(=C(C=C23)O)O)Cl)C
Computed descriptors from PubChem (CID 133538), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il