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Chemical structure of SKF-83566

GC61281

SKF-83566

Also known as 8-bromo-3-methyl-5-phenyl-1,2,4,5-tetrahydro-3-benzazepin-7-ol

SKF-83566 is a potent,?blood-brain permeable and orally active D1-like dopamine receptor (D1DR)?antagonist and a weaker competitive antagonist at the vascular 5-HT2?receptor (Ki=11 nM)

ChemicalCAS99295-33-7MW332.23FormulaC17H18BrNO
CAS number
99295-33-7
Molecular weight
332.23
Formula
C17H18BrNO
Solubility
DMSO ： 33·33 mg/mL (100·32 mM; Need ultrasonic)
InChIKey
XFTVOHWWEQGXLS-UHFFFAOYSA-N
Catalogue number
GC61281
Brand
GLPBIO
Computed properties PubChem CID 1243 · XLogP 4 · TPSA 23.5 Ų · H-bond donors 1
XLogP
4
TPSA
23.5 Ų
H-bond donors
1
H-bond acceptors
2
Rotatable bonds
1
Heavy atoms
20

SMILES CN1CCC2=CC(=C(C=C2C(C1)C3=CC=CC=C3)O)Br

Computed descriptors from PubChem (CID 1243), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
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Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.