GC69907
SK-575
Also known as N-[2-[[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindol-4-yl]amino]ethyl]-12-[4-[2-fluoro-5-[(4-oxo-3H-phthalazin-1-yl)methyl]benzoyl]piperazin-1-yl]-12-oxododecanamide
SK-575 is an efficient and specific protein-hydrolyzing targeted chimeric molecule (PROTAC) PARP1 degrader with an IC50 of 2·30 nM· SK-575 can effectively inhibit the growth of cancer cells carrying BRCA1/2 mutations
ChemicalCAS2523016-96-6MW876.97FormulaC47H53FN8O8
- CAS number
- 2523016-96-6
- Molecular weight
- 876.97
- Formula
- C47H53FN8O8
- Solubility
- DMSO ： 100 mg/mL (114·03 mM; Need ultrasonic)
- InChIKey
- HPBWDZVXFSTVMR-UHFFFAOYSA-N
- Catalogue number
- GC69907
- Brand
- GLPBIO
Computed properties PubChem CID 162664494 · XLogP 5 · TPSA 207 Ų · H-bond donors 4
- XLogP
- 5
- TPSA
- 207 Ų
- H-bond donors
- 4
- H-bond acceptors
- 11
- Rotatable bonds
- 19
- Heavy atoms
- 64
SMILES C1CC(=O)NC(=O)C1N2C(=O)C3=C(C2=O)C(=CC=C3)NCCNC(=O)CCCCCCCCCCC(=O)N4CCN(CC4)C(=O)C5=C(C=CC(=C5)CC6=NNC(=O)C7=CC=CC=C76)F
Computed descriptors from PubChem (CID 162664494), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il