GC69804
RBN-3143
Also known as 7-[(1-acetylpiperidin-4-yl)methoxy]-5-fluoro-2-(oxan-4-ylsulfanylmethyl)-3H-quinazolin-4-one
RBN-3143 is an effective NAD+ competitive catalytic PARP14 inhibitor with an IC50 value of 4 nM· RBN-3143 inhibits PARP14-mediated ADP-ribosylation and stabilizes PARP14 in cell lines· RBN-3143 is used for research on lung inflammation
ChemicalCAS2360853-16-1MW449.54FormulaC22H28FN3O4S
- CAS number
- 2360853-16-1
- Molecular weight
- 449.54
- Formula
- C22H28FN3O4S
- Solubility
- DMSO ： 12·5 mg/mL (27·81 mM; ultrasonic and warming and heat to 80°C)
- InChIKey
- LLXIEISWIFSUBQ-UHFFFAOYSA-N
- Catalogue number
- GC69804
- Brand
- GLPBIO
Computed properties PubChem CID 138697188 · XLogP 2.1 · TPSA 106 Ų · H-bond donors 1
- XLogP
- 2.1
- TPSA
- 106 Ų
- H-bond donors
- 1
- H-bond acceptors
- 7
- Rotatable bonds
- 6
- Heavy atoms
- 31
SMILES CC(=O)N1CCC(CC1)COC2=CC3=C(C(=C2)F)C(=O)NC(=N3)CSC4CCOCC4
Computed descriptors from PubChem (CID 138697188), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.
Ordering in Israel
- Lead time
- Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
- Pricing
- Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
- Documents
- Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
- Who we serve
- Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.
- Questions
- WhatsApp · +972-55-990-7576 · orders@labo.co.il