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Chemical structure of RB-3

GC65605

RB-3

Also known as 3-(5-chloro-1H-indol-4-yl)-5-(1H-indol-4-yl)-4-propan-2-yl-1H-pyrrole-2-carboxylic acid

RB-3, a PRC1 inhibitor, binds to RING1B-BMI1f, with a Kd of 2·8 μM

ChemicalCAS2396639-11-3MW417.89FormulaC24H20ClN3O2
CAS number
2396639-11-3
Molecular weight
417.89
Formula
C24H20ClN3O2
InChIKey
IUEFQUANJWCUNT-UHFFFAOYSA-N
Catalogue number
GC65605
Brand
GLPBIO
Computed properties PubChem CID 146315785 · XLogP 5.9 · TPSA 84.7 Ų · H-bond donors 4
XLogP
5.9
TPSA
84.7 Ų
H-bond donors
4
H-bond acceptors
2
Rotatable bonds
4
Heavy atoms
30

SMILES CC(C)C1=C(NC(=C1C2=C(C=CC3=C2C=CN3)Cl)C(=O)O)C4=C5C=CNC5=CC=C4

Computed descriptors from PubChem (CID 146315785), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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