Loading...
Chemical structure of PT-262

GC69776

PT-262

Also known as 7-chloro-6-piperidin-1-ylquinoline-5,8-dione

PT-262 is an effective ROCK inhibitor with an IC50 value of approximately 5 μM· PT-262 induces loss of mitochondrial membrane potential and increases activation of caspase-3 and cell apoptosis· PT-262 inhibits phosphorylation of ERK and CDC2 through a p53-independent pathway· PT-262 blocks cellular cytoskeleton function and cell migration· PT-262 has anti-cancer activity

ChemicalCAS86811-36-1MW276.72FormulaC14H13ClN2O2
CAS number
86811-36-1
Molecular weight
276.72
Formula
C14H13ClN2O2
Solubility
DMSO ： 100 mg/mL (361·38 mM; Need ultrasonic)
InChIKey
XBHXHCMFAUSIKK-UHFFFAOYSA-N
Catalogue number
GC69776
Brand
GLPBIO
Computed properties PubChem CID 12424014 · XLogP 2.7 · TPSA 50.3 Ų · H-bond donors 0
XLogP
2.7
TPSA
50.3 Ų
H-bond donors
0
H-bond acceptors
4
Rotatable bonds
1
Heavy atoms
19

SMILES C1CCN(CC1)C2=C(C(=O)C3=C(C2=O)C=CC=N3)Cl

Computed descriptors from PubChem (CID 12424014), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.