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Chemical structure of PT-2385

GC32680

PT-2385

Also known as 3-[[(1S)-2,2-difluoro-1-hydroxy-7-methylsulfonyl-1,3-dihydroinden-4-yl]oxy]-5-fluorobenzonitrile

PT-2385 is a selective HIF-2α inhibitor with a Ki of less than 50 nM

ChemicalCAS1672665-49-4MW383.34FormulaC17H12F3NO4S
CAS number
1672665-49-4
Molecular weight
383.34
Formula
C17H12F3NO4S
Solubility
DMSO : ≥ 50 mg/mL (130·43 mM)
InChIKey
ONBSHRSJOPSEGS-INIZCTEOSA-N
Catalogue number
GC32680
Brand
GLPBIO
Computed properties PubChem CID 91754484 · XLogP 2.4 · TPSA 95.8 Ų · H-bond donors 1
XLogP
2.4
TPSA
95.8 Ų
H-bond donors
1
H-bond acceptors
8
Rotatable bonds
3
Heavy atoms
26

SMILES CS(=O)(=O)C1=C2[C@@H](C(CC2=C(C=C1)OC3=CC(=CC(=C3)C#N)F)(F)F)O

Computed descriptors from PubChem (CID 91754484), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
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Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.