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Chemical structure of MTX-23

GC69744

MTX-23

Also known as (2S,4R)-1-[(2S)-2-[5-[[2-[2,3-difluoro-6-(2-morpholin-4-yl-1,3-thiazol-4-yl)phenoxy]acetyl]amino]pentanoylamino]-3,3-dimethylbutanoyl]-4-hydroxy-N-[(1S)-1-[4-(4-methyl-1,3-thiazol-5-yl)phenyl]ethyl]pyrrolidine-2-carboxamide

MTX-23 is an AR-based PROTAC· MTX-23 inhibits CaP cell proliferation by degrading AR-V7 and AR-FL· MTX-23 induces apoptosis in cells

ChemicalCAS2488296-74-6MW882.05FormulaC43H53F2N7O7S2
CAS number
2488296-74-6
Molecular weight
882.05
Formula
C43H53F2N7O7S2
Solubility
DMSO ： 100 mg/mL (113·37 mM; Need ultrasonic)
InChIKey
JOZGICGAZBMCJF-JMSDHYLISA-N
Catalogue number
GC69744
Brand
GLPBIO
Computed properties PubChem CID 154612215 · XLogP 5.3 · TPSA 232 Ų · H-bond donors 4
XLogP
5.3
TPSA
232 Ų
H-bond donors
4
H-bond acceptors
14
Rotatable bonds
17
Heavy atoms
61

SMILES CC1=C(SC=N1)C2=CC=C(C=C2)[C@H](C)NC(=O)[C@@H]3C[C@H](CN3C(=O)[C@H](C(C)(C)C)NC(=O)CCCCNC(=O)COC4=C(C=CC(=C4F)F)C5=CSC(=N5)N6CCOCC6)O

Computed descriptors from PubChem (CID 154612215), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.