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Chemical structure of Pelecopan

GC69684

Pelecopan

Also known as 2-[2-[[7-[2-(aminomethyl)-3-fluoro-4-pyridinyl]-1-benzofuran-5-yl]methoxy]phenyl]acetic acid

Pelecopan (BCX9930) is an effective and selective complement factor D inhibitor with oral activity· Its IC50 value is 14·3 nM· Pelecopan can target complement factor D to prevent intravascular and extravascular hemolysis in PNH, as well as other diseases mediated by alternative pathways

ChemicalCAS2378380-49-3MW406.41FormulaC23H19FN2O4
CAS number
2378380-49-3
Molecular weight
406.41
Formula
C23H19FN2O4
Solubility
DMSO : 100 mg/mL (246·06 mM; Need ultrasonic)
InChIKey
AUARNXJEAZFQCQ-UHFFFAOYSA-N
Catalogue number
GC69684
Brand
GLPBIO
Computed properties PubChem CID 139560984 · XLogP 0.5 · TPSA 98.6 Ų · H-bond donors 2
XLogP
0.5
TPSA
98.6 Ų
H-bond donors
2
H-bond acceptors
7
Rotatable bonds
7
Heavy atoms
30

SMILES C1=CC=C(C(=C1)CC(=O)O)OCC2=CC(=C3C(=C2)C=CO3)C4=C(C(=NC=C4)CN)F

Computed descriptors from PubChem (CID 139560984), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

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