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Chemical structure of MSC-1186

GC69507

MSC-1186

Also known as N-[3-[[[2-(5-chloro-4-fluoro-1H-benzimidazol-2-yl)pyrimidin-4-yl]amino]methyl]-2-pyridinyl]-N-methylmethanesulfonamide

MSC-1186 is a highly selective pan-SRPK inhibitor· It has activity against SRPK1, SRPK2, and SRPK3 with IC50 values of 2·7 nM, 81 nM, and 0·6 nM respectively· MSC-1186 can be used for cancer research

ChemicalCAS2871698-23-4MW461.9FormulaC19H17ClFN7O2S
CAS number
2871698-23-4
Molecular weight
461.9
Formula
C19H17ClFN7O2S
Solubility
DMSO ： 125 mg/mL (270·62 mM; Need ultrasonic)
InChIKey
WBFJDKLBAAHKIL-UHFFFAOYSA-N
Catalogue number
GC69507
Brand
GLPBIO
Computed properties PubChem CID 162368309 · XLogP 2.4 · TPSA 125 Ų · H-bond donors 2
XLogP
2.4
TPSA
125 Ų
H-bond donors
2
H-bond acceptors
9
Rotatable bonds
6
Heavy atoms
31

SMILES CN(C1=C(C=CC=N1)CNC2=NC(=NC=C2)C3=NC4=C(N3)C=CC(=C4F)Cl)S(=O)(=O)C

Computed descriptors from PubChem (CID 162368309), public domain. Identity cross-checked against the supplier's molecular formula and weight — verify before use.

Ordering in Israel

Lead time
Ships from the manufacturer to your lab in 8–14 business days; customs and cold chain handled by LABO Scientific.
Pricing
Quoted in ILS, excl. VAT. Add the item to your quote and we confirm the final price, usually the same business day.
Documents
Lot certificate of analysis and manufacturer SDS are emailed with your order confirmation.
Who we serve
Universities, hospitals and biotech companies across Israel. Research use only — not for diagnostic or therapeutic use.